TNFRSF1A

TNFRSF1A
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1EXT, 1FT4, 1ICH, 1NCF, 1TNR
Dynodwyr
Cyfenwau	TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60, tumor necrosis factor receptor superfamily member 1A, TNF receptor superfamily member 1A
Dynodwyr allanol	OMIM: 191190 HomoloGene: 828 GeneCards: TNFRSF1A
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • tumor necrosis factor-activated receptor activity; • tumor necrosis factor binding; • identical protein binding;
Cydrannau o'r gell	• integral component of membrane; • Golgi apparatus; • bilen; • Golgi membrane; • receptor complex; • Cellbilen; • integral component of plasma membrane; • extracellular region; • cell surface; • mitocondria; • membrane raft; • extracellular space; • tumor necrosis factor receptor superfamily complex;
Prosesau biolegol	• regulation of apoptotic process; • prostaglandin metabolic process; • defense response; • positive regulation of ceramide biosynthetic process; • positive regulation of inflammatory response; • regulation of tumor necrosis factor-mediated signaling pathway; • tumor necrosis factor-mediated signaling pathway; • response to lipopolysaccharide; • cellular response to mechanical stimulus; • death-inducing signaling complex assembly; • regulation of cell population proliferation; • defense response to bacterium; • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response; • intrinsic apoptotic signaling pathway in response to DNA damage; • positive regulation of I-kappaB kinase/NF-kappaB signaling; • GO:0022415 viral process; • I-kappaB kinase/NF-kappaB signaling; • negative regulation of inflammatory response; • regulation of establishment of endothelial barrier; • extrinsic apoptotic signaling pathway via death domain receptors; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • GO:0072468 signal transduction; • GO:0097285 apoptotic process; • inflammatory response; • cell surface receptor signaling pathway; • positive regulation of tyrosine phosphorylation of STAT protein; • protein localization to plasma membrane; • cytokine-mediated signaling pathway; • aortic valve development; • pulmonary valve development; • negative regulation of extracellular matrix constituent secretion; • negative regulation of cardiac muscle hypertrophy; • positive regulation of apoptotic process involved in morphogenesis;
	Sources:Amigo / QuickGO
Orthologau
	7132
	n/a
	ENSG00000067182
	n/a
	P19438
	n/a
	NM_001065; NM_001346091; NM_001346092
	n/a
	NP_001056; NP_001333020; NP_001333021
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TNFRSF1A yw TNFRSF1A a elwir hefyd yn Tumor necrosis factor receptor superfamily member 1A a TNF receptor superfamily member 1a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12p13.31.^[2]

[1] "Human PubMed Reference:".

[2] TNFRSF1A - Cronfa NCBI

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